Follow this step-by-step video to create 1099s for your business. You can either have QuickBooks auto-fill your forms, or manually fill them in yourself. Both options let you e-file with the IRS in the end.
After you e-file with the IRS, you can email your 1099 vendors an invite so they can download their 1099. Note that 1099s are due to contractors by January 31.